POINTS TO CONSIDER BEFORE SELL?
 The decision of when and  how much to buy is a relatively easy task as against when and what to sell. But  then here are some pointers, which will assist you in deciding when to sell.  Keep in mind that these parameters are not independent pointers but when all of  them scream together then its time to step in and sell.
 1. When they no longer meet the needs of the investor or when  you had bought a stock expecting a specific announcement and it didn't occur.  Most Pharma stocks fall into this category. Sometimes when they are on the verge  of medical breakthroughs as they so claim, in reality if doesn’t materialize  into real medicines; the stock will go down because every one else is selling.  It's then time to sell yours too immediately, as it didn’t meet your need.
 2. When the price in the market for the securities is an  historical high. It's done even better than you initially imagined, went up five  or ten times what you paid for it. When you get such a spectacularly performing  stock, the last thing you should do is to sell all of it. Don't be afraid of  making big money. While you liquidate a part of your holding in the stock to get  back your principal and some neat profit, hold on to the rest to get you more  money; unless there is some fundamental shift necessitating to sell your whole  position. To repeat do not sell your whole position.
 3. When the future expectations no longer support the price of  the stock or when yields fall below the satisfactory level. You need to  constantly monitor the various ratios and data points over time, not just when  you buy the stock but also when you sell. When most ratios suggest the stock is  getting expensive, as determined by your initial evaluation, then you need to  sell the stock. But don't sell if only one of your variables is out of track.  There should be a number of them screaming that the stock is fully valued.
 4. When other alternatives are more attractive than the stocks  held, then liquidate your position in a stock which is least performing and  reinvest the same in a new buy.
 5. When there is tax advantage in the sale for the investor. If  you have made a capital gain somewhere, you can safely buy a stock before  dividend announcements i.e. at cum-interest prices and sell it after dividend  pay out at ex-interest prices, which will be way below the price at which you  had bought the stock. This way the capital loss that you make out of the buy and  sell can be offset against the capital gain that you had made elsewhere and will  hence cut your taxes on it.
 6. Sell if there has been a dramatic change in the direction of  the company. Its usually a messy problem when a company successful in one  business decides to enter another unrelated venture. Such a decision even though  would step up the price initially due to the exuberant announcements, it would  begin to fall heavily after a short span. This is because the new venture  usually squeezes the successful venture of its reserves and reinvesting  capability, thus hurting its future earnings capability. 
 7. If the earnings and if they aren't improving over two to  three quarters, chuck out the stock from your portfolio. To get a higher price  on a stock, it needs to constantly improve earnings, not just match past  quarters. However, as an investor, you need to read the earnings announcements  carefully and determine if there are one-time charges that are hurting current  earnings for the benefit of future earnings. 
 8. Cut losses at the right level. But do not sell on panic. The  usual rule for retail investor is to sell if a stock falls 8% below the purchase  price. If you don't cut losses quickly, sooner or later you'll suffer some very  large losses. Cutting losses at 8% will always allow investors to survive to  invest another day.